Sentences with Up Against

The environmental activists knew they were up against powerful industries that resisted change.

The scientist was up against skepticism from peers when presenting his unconventional theory.

The ambitious project was up against budget constraints that required creative solutions.

The community was up against the aftermath of a natural disaster, requiring swift recovery efforts.

The wildlife photographer knew he was up against unpredictable animal behavior in the wilderness.

The startup company was up against financial instability in its early stages of development.

The healthcare system was up against the demand for efficient solutions in times of a health crisis.